Fast Kinetics

G-protein couple receptors are an important highly druggable gene family. Upon receptor activation, a wide range of second messengers are activated to illicit many different cellular responses. These second messengers include the mobilization of Ca²⁺, increase or reduction of intracellular cAMP, production of diacylglycerol and phospatidylinositols. These second messengers can be monitored kinetically using fluorescent reagents and biosensors.

GPCR Signaling Pathways

Application Notes:

• Live Cell Imaging of GPCR Dependent Second-Messenger Systems
• Characterizing Calcium Mobilization using Kinetic Live Cell Imaging

Visual Abstracts (.mp4):

BioTek’s Visual Abstracts are brief animated presentations describing the Augmented Microscopy workflow of a specific application.

Related Products:

• Lionheart FX Automated Microscope
• Cytation 5 Cell Imaging Multi-Mode Reader
• Cytation 1 Cell Imaging Multi-Mode Reader

Learn more about GPCR Second Messengers applications - search our Application Notes and technical documentation in Resources.

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